Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 237
interventional 194
Observational 38
Registry 5

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type Study_Count
Procedure 40
Drug|placebo 37
Drug 25
Other 19
Device 15
Drug|Procedure 12
Device|Procedure 6
Drug|placebo|Procedure 5
Biological|Procedure 4
Dietary Supplement|placebo 4
Biological 3
Biological|Drug|Procedure 2
Device|Other 2
Other|Procedure 2
Behavioral|Drug|Procedure 1
Behavioral|Procedure 1
Biological|Device|Genetic 1
Biological|Other|Procedure 1
Biological|placebo 1
Combination Product 1
Device|Drug|Other 1
Device|placebo 1
Diagnostic Test 1
Diagnostic Test|Drug|Procedure 1
Dietary Supplement|Drug 1
Dietary Supplement|Other 1
Dietary Supplement|placebo|Procedure 1
Drug|Other|Procedure 1
Genetic 1
Other|placebo 1
Other|Radiation 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
NA 73
India 35
Brazil 15
Egypt 10
United States 10
Turkey 7
Chile 3
France 3
Israel 3
Malaysia 3
Belgium 2
Canada 2
China 2
Iran, Islamic Republic of 2
Italy 2
Japan 2
Korea, Republic of 2
Pakistan 2
Spain 2
Australia|Italy|Spain|United Kingdom 1
Austria 1
Colombia 1
Germany|Netherlands|United Kingdom 1
Greece 1
Iraq 1
Poland 1
Romania 1
Saudi Arabia 1
Sweden 1
Switzerland 1
Syrian Arab Republic 1
United Arab Emirates 1
United Kingdom 1

Sites per Study

Site_count Study_Count
1 180
2 8
3 2
8 1
9 1
10 1
26 1

Phase

Phase Study_Count
N/A 90
Phase 4 33
Phase 2/Phase 3 26
Phase 2 19
Phase 3 13
Phase 1/Phase 2 6
Early Phase 1 5
Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 10
2 122
3 41
4 13
5 2
6 3
NA 3

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 18.0 10.00000 12.0 10.00 16.00000 2.0 28.0000 10.00000
1st Qu. 25.0 29.25000 22.5 21.00 30.00000 51.0 31.7500 40.00000
Median 30.0 43.00000 33.0 27.00 43.00000 85.0 57.0000 50.00000
Mean 41.8 61.01111 33.0 27.50 64.83333 106.0 140.0833 51.27273
3rd Qu. 60.0 60.00000 43.5 30.75 75.00000 94.5 109.5000 63.00000
Max. 76.0 800.00000 54.0 50.00 275.00000 1000.0 602.0000 110.00000

Trial Group Type

group_type Group_Count
Experimental 163
Active Comparator 157
Placebo Comparator 76
No Intervention 24
Other 24
Sham Comparator 13
NA 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 164
Single Group Assignment 20
Crossover Assignment 7
Factorial Assignment 1
Sequential Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 162
Prevention 8
Diagnostic 7
Supportive Care 7
Other 3
Screening 3
Basic Science 2
Health Services Research 2

Observational Studies

Studies by Country

Country Study_Count
NA 11
India 7
Turkey 6
Syrian Arab Republic 4
France 3
Brazil 1
Denmark 1
Italy 1
Italy|United Kingdom 1
Saudi Arabia 1
United Kingdom 1
United States 1

Sites per Study

Site_count Study_Count
1 34
2 4

Enrollment Metrics

Measure Observational
Min 30.0000
1st Qu 52.5000
Median 70.0000
Mean 133.3421
3rd Qu 84.0000
Max 2000.0000

Observation Model

observational_model Study_Count
Case-Control 16
Case Control 10
Other 8
Cohort 4

Time Perspective

time_perspective Study_Count
Cross-Sectional 15
Other 8
Retrospective 8
Prospective 7

Registries

Studies by Country

Country Study_Count
Turkey 2
Egypt 1
India 1
NA 1

Sites per Study

Site_count Study_Count
1 5

Enrollment Metrics

Measure Registries
Min 30.0
1st Qu 54.0
Median 80.0
Mean 139.4
3rd Qu 88.0
Max 445.0

Registry Model

observational_model Study_Count
Case-Control 4
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 3
Cross-Sectional 2

Follow-up

target_duration Study_Count
1 Day 2
1 Month 1
4 Months 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT02627534 Effects of Adjunct Photodynamic Therapy in the Treatment of Type 2 Diabetic Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02627534 Completed Universidade Estadual Paulista Júlio de Mesquita Filho 2015-03-31
NCT03368430 Melatonin as an Adjunctive Therapy for Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT03368430 Completed Mansoura University 2017-06-08
NCT03364751 Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome https://ClinicalTrials.gov/show/NCT03364751 Completed Philip Morris Products S.A. 2018-12-21
NCT03343366 Glycemic Control in T2DM Through Non-Surgical Periodontal Therapy https://ClinicalTrials.gov/show/NCT03343366 Enrolling by invitation Dow University of Health Sciences 2019-12-31
NCT03311243 Periodontal Therapy in Thalassemia Major Patients https://ClinicalTrials.gov/show/NCT03311243 Completed King Saud University 2017-04-10
NCT03308019 Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers. https://ClinicalTrials.gov/show/NCT03308019 Completed King Saud University 2017-07-02
NCT03262077 Dose Parameters for Photodynamic Therapy on Periodontal Disease https://ClinicalTrials.gov/show/NCT03262077 Completed University of Nove de Julho 2017-06-26
NCT03241511 Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT03241511 Recruiting UConn Health 2020-04-30
NCT03227367 Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials. https://ClinicalTrials.gov/show/NCT03227367 Completed Meenakshi Ammal Dental College and Hospital 2016-04-13
NCT03204097 Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03204097 Completed Government Dental College and Research Institute, Bangalore 2017-02-28
NCT03204071 Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03204071 Completed Government Dental College and Research Institute, Bangalore 2017-02-28
NCT03204058 Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03204058 Completed Government Dental College and Research Institute, Bangalore 2017-02-23
NCT03203746 Gingival Crevicular Fluid Levels of Protein Carbonyl Following the Use of Lycopene in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03203746 Completed Ain Shams University 2016-11-10
NCT03178526 The Effect of Lovastatin Gel in the Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03178526 Completed Islamic Azad University, Tehran 2016-01-13
NCT03043196 1.2% Rosuvastatin Gel As A Local Agent In Smokers With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03043196 Completed Government Dental College and Research Institute, Bangalore 2016-04-30
NCT03043066 Serum TRAP-5b Levels in Patients With Generalized Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03043066 Completed Meenakshi Ammal Dental College and Hospital 2016-07-31
NCT03039244 Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers https://ClinicalTrials.gov/show/NCT03039244 Completed University of Sao Paulo 2016-12-01
NCT03025204 Enamel Matrix Proteins in the Treatment of Intrabony Defects in Patients With Aggressive and Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03025204 Completed University of Campinas, Brazil 2018-04-30
NCT03005886 The Effect of Periodontal Therapy in Chronic Periodontitis Patients With and Without Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT03005886 Completed Gazi University 2010-08-31
NCT02985099 1.2% Rosuvastatin Subgingivally Delivered In Chronic Periodontitis With Type 2 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02985099 Completed Government Dental College and Research Institute, Bangalore 2016-07-31
NCT02977351 Determining the Relationship Between the Atherosclerosis and Periodontopathogenic Microorganisms https://ClinicalTrials.gov/show/NCT02977351 Completed Izmir Katip Celebi University 2015-01-31
NCT02967861 Effect of Pranayama on Periodontal Health https://ClinicalTrials.gov/show/NCT02967861 Completed Meenakshi Ammal Dental College and Hospital 2016-07-31
NCT02954393 Amoxicillin and Metronidazole During Periodontal Treatment https://ClinicalTrials.gov/show/NCT02954393 Active, not recruiting University of Guarulhos 2019-12-31
NCT02930356 Effect of Tooth Cleaning in Smokers and Non Smokers With Gum Disease. https://ClinicalTrials.gov/show/NCT02930356 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2016-04-30
NCT02903108 Clinical Efficacy of 0.75% Boric Acid Gel in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02903108 Completed Government Dental College and Research Institute, Bangalore 2015-10-31
NCT02901743 Effect on Teeth and Gum Cleaning in Patients With Gum and Kidney Disease https://ClinicalTrials.gov/show/NCT02901743 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2015-06-30
NCT02898675 Advantages of Autologous Platelet-Rich Fibrin Membrane on Growth Factor Levels and Periodontal Healing https://ClinicalTrials.gov/show/NCT02898675 Completed Ataturk University 2015-06-30
NCT02890771 Efficacy of Turmeric in Gingival Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patient https://ClinicalTrials.gov/show/NCT02890771 Completed Government College of Dentistry, Indore 2016-12-31
NCT02886676 Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects https://ClinicalTrials.gov/show/NCT02886676 Completed Tatyasaheb Kore Dental College 2016-05-31
NCT02880397 Garcinia Mangostana L.Pericarp Gel as a Local Drug Delivery in Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02880397 Completed Meenakshi Ammal Dental College and Hospital 2015-11-30
NCT02875769 Pre-procedural Mouthwash in Reducing Bacteria in Dental Aerosols https://ClinicalTrials.gov/show/NCT02875769 Completed University of Guarulhos 2015-03-31
NCT02875470 Burs Versus Curettes in Root Planing. https://ClinicalTrials.gov/show/NCT02875470 Completed Ege University 2014-08-31
NCT02861326 RELATIONSHIP BETWEEN INITIAL PROBING DEPTH AND CHANGES IN CLINICAL PARAMETERS FOLLOWING NON-SURGICAL PERIODONTAL TREATMENT IN CHRONIC PERIODONTITIS PATIENTS https://ClinicalTrials.gov/show/NCT02861326 Completed Marmara University 2015-01-31
NCT02836314 Clinical and Radiological Effect Of Platelet Rich Fibrin on the Healing of Periodontal Intrabony Periodontal Defects https://ClinicalTrials.gov/show/NCT02836314 Completed Baskent University 2012-12-31
NCT02830113 Metabolic Effects of Treatment of Chronic Periodontitis in Non-diabetic Subjects https://ClinicalTrials.gov/show/NCT02830113 Completed Yaounde Central Hospital 2015-05-31
NCT02817152 Low-level Laser Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics https://ClinicalTrials.gov/show/NCT02817152 Completed Universidade Estadual Paulista Júlio de Mesquita Filho 2015-09-30
NCT02800902 Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02800902 Completed Government Dental College and Research Institute, Bangalore 2016-02-29
NCT02794506 Propolis Improves Glycemic Control in Subjects With Type 2 Diabetes and Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02794506 Completed Mansoura University 2014-12-31
NCT02793453 Antimicrobial Peptides in Periodontitis https://ClinicalTrials.gov/show/NCT02793453 Completed CHU de Reims 2016-03-23
NCT02767115 Grape Seeds Extract Gel as an Adjunct for the Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02767115 Completed Riyadh Colleges of Dentistry and Pharmacy 2015-09-30
NCT02764879 Effect of Omega 3 on Periodontitis in Postmenopausal Women https://ClinicalTrials.gov/show/NCT02764879 Completed October 6 University 2015-01-31
NCT02735395 Dose and Duration of Metronidazole and Amoxicillin for Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02735395 Active, not recruiting University of Guarulhos 2014-05-31
NCT02734784 Treatment of Chronic Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy https://ClinicalTrials.gov/show/NCT02734784 Completed University of Sao Paulo 2015-11-30
NCT02726646 Evaluation of Local Doxycycline in Smokers With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02726646 Completed University of Campinas, Brazil 2016-11-30
NCT02719587 Dietary Supplementation With Low-Dose Omega-3 Reduces Salivary TNF-α Levels in Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02719587 Completed Ondokuz Mayıs University 2009-12-31
NCT02705885 IgY Efficacy on Periodontitis Patients https://ClinicalTrials.gov/show/NCT02705885 Completed Immunology Research Institute in Gifu 2014-08-31
NCT02697539 Plaque Formation Rate and Toothpaste https://ClinicalTrials.gov/show/NCT02697539 Completed University Hospital Muenster 2011-09-30
NCT02692079 The Effectiveness of Titanium-Prepared Platelet-Rich Fibrin on Angiogenic Biomarkers in Gingival Crevicular Fluid https://ClinicalTrials.gov/show/NCT02692079 Completed Kırıkkale University 2014-09-30
NCT02679209 Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft in Periodontal Intrabony Defects https://ClinicalTrials.gov/show/NCT02679209 Completed Cairo University 2017-05-31
NCT02676362 Methodological Evaluation of Gingival Crevicular Fluid Volume and Elastase Level https://ClinicalTrials.gov/show/NCT02676362 Completed Baskent University 2008-12-31
NCT02672384 Chronic Periodontitis in Critically Ill Patients: Diagnosis and Epidemiology https://ClinicalTrials.gov/show/NCT02672384 Completed University Hospital, Brest 2018-10-14
NCT02666573 Photodynamic Therapy During Supportive Periodontal Therapy https://ClinicalTrials.gov/show/NCT02666573 Completed National University, Singapore 2014-12-31
NCT02657096 Decontaminant Agent in the Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02657096 Completed University of Messina 2015-05-31
NCT02652026 Effect of Non-surgical Periodontal Treatment on HbA1c in Type 2 Diabetic Patients https://ClinicalTrials.gov/show/NCT02652026 Completed University of Barcelona 2015-09-30
NCT02645669 Effect of a Locally Delivered Probiotic in Periodontitis https://ClinicalTrials.gov/show/NCT02645669 Completed SVS Institute of Dental Sciences 2015-03-31
NCT02645227 Platelet-rich Fibrin With 1.2% Rosuvastatin in Chronic Periodontitis Treatment https://ClinicalTrials.gov/show/NCT02645227 Completed Government Dental College and Research Institute, Bangalore 2015-10-31
NCT02641210 Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin https://ClinicalTrials.gov/show/NCT02641210 Completed Federal University of Maranhao 2015-06-30
NCT02639572 Evaluation of SilOss® in Periodontal Surgery https://ClinicalTrials.gov/show/NCT02639572 Completed SVS Institute of Dental Sciences 2014-08-31
NCT02638740 To Study the Beneficial Effect of Mustard Oil and Salt Massaging With Oral Prophylaxis in Patients With Gum Diseases https://ClinicalTrials.gov/show/NCT02638740 Completed Government College of Dentistry, Indore 2015-12-31
NCT02636114 Effect of Scaling and Root Planing on Serum Renal Function Markers in Chronic Periodontitis Subjects. https://ClinicalTrials.gov/show/NCT02636114 Completed Maharashtra University of Health Sciences 2015-02-28
NCT02632981 IL-32 Levels in Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02632981 Completed Bulent Ecevit University 2015-05-31
NCT02600520 Comparison of Rosuvastatin With Atorvastatin in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02600520 Completed Government Dental College and Research Institute, Bangalore 2015-05-31
NCT02596581 Chemerin and IL-6 Levels in Diabetes and Periodontitis https://ClinicalTrials.gov/show/NCT02596581 Completed Bulent Ecevit University 2015-05-31
NCT02594605 Applied The Platelet Rich Fibrin in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02594605 Completed Ataturk University 2013-06-30
NCT02585596 A Phase II Clinical Trial of YH23537 in Patients With Chronic Periodontal Disease. https://ClinicalTrials.gov/show/NCT02585596 Completed Yuhan Corporation 2016-12-28
NCT02583841 “Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial.” https://ClinicalTrials.gov/show/NCT02583841 Completed Tatyasaheb Kore Dental College 2015-03-31
NCT02563171 Gingival Crevicular Fluid Vaspin and Omentin Levels in Obese Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02563171 Completed Bulent Ecevit University 2015-05-31
NCT02544347 Gingival Crevicular Fluid Vaspin and Omentin Levels in Type 2 Diabetic Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02544347 Completed Bulent Ecevit University 2015-05-31
NCT02538224 Efficacy of Subgingivally Delivered Doxycycline Plus Ketoprofen Gel as an Adjunct to Non-surgical Periodontal Treatment https://ClinicalTrials.gov/show/NCT02538224 Completed Islamic Azad University, Tehran 2014-02-28
NCT02531555 Clinical Efficacy Of 810 Nanometer Diode Laser As An Adjunct To Mechanical Periodontal Treatment Of Residual Periodontal Pockets https://ClinicalTrials.gov/show/NCT02531555 Completed Marmara University 2014-04-30
NCT02518152 Platelet Rich Fibrin+1% Alendronate in Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02518152 Completed Government Dental College and Research Institute, Bangalore 2015-06-30
NCT02516111 Comparison of Autologous PRF, 1% Alendronate and 1.2% Atorvastatin Gel in Chronic Periodontitis Treatment https://ClinicalTrials.gov/show/NCT02516111 Completed Government Dental College and Research Institute, Bangalore 2015-05-31
NCT02507596 Evaluation of Nano-crystalline Hydroxyapatite Silica Gel in Management of Periodontal Intrabony Defects https://ClinicalTrials.gov/show/NCT02507596 Recruiting Cairo University 2019-10-31
NCT02462993 Local Drug Delivery of Aloe Vera Gel in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02462993 Completed Dr. D. Y. Patil Dental College & Hospital 2014-08-31
NCT02461667 Alendronate Compared to Metformin in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02461667 Completed Government Dental College and Research Institute, Bangalore 2015-03-31
NCT02455869 Comparison of Alendronate With Atorvastatin in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02455869 Completed Government Dental College and Research Institute, Bangalore 2015-03-31
NCT02449005 Autologous Alveolar Bone Marrow Mesenchymal Stem Cells for the Reconstruction of Infrabony Periodontal Defects https://ClinicalTrials.gov/show/NCT02449005 Completed Aristotle University Of Thessaloniki 2016-09-30
NCT02442453 Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients https://ClinicalTrials.gov/show/NCT02442453 Completed Tatyasaheb Kore Dental College 2014-11-30
NCT02437747 Locally Delivered Aloe Vera Gel in the Treatment of Chronic Periodontitis Patients With Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02437747 Completed Dr. D. Y. Patil Dental College & Hospital 2015-03-31
NCT02430519 Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation Defects https://ClinicalTrials.gov/show/NCT02430519 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2013-05-31
NCT02390687 Evaluation of the Efficacy of Probiotics in Chronic Periodontitis Patients https://ClinicalTrials.gov/show/NCT02390687 Completed Next Gen Pharma India Pvt. Ltd. 2016-09-30
NCT02386033 Atorvastatin in the Treatment of Mandibular Degree II Furcation Defects https://ClinicalTrials.gov/show/NCT02386033 Completed Government Dental College and Research Institute, Bangalore 2014-07-31
NCT02386020 Aloe Vera in Chronic Periodontitis With Type 2 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02386020 Completed Government Dental College and Research Institute, Bangalore 2014-12-31
NCT02368678 “Study of Halitosis in Patients With Advanced Chronic Periodontitis” https://ClinicalTrials.gov/show/NCT02368678 Completed Federal University of Minas Gerais 2014-05-31
NCT02355977 The Response of Pathogens to the Respective or Combined Treatment of SRP and Local Minocycline in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02355977 Completed Zhejiang University 2014-09-30
NCT02329353 Effect of Probiotics on Chronic Periodontitis in Smoker and Non- Smokers https://ClinicalTrials.gov/show/NCT02329353 Completed Next Gen Pharma India Pvt. Ltd. 2016-11-30
NCT02325570 Evaluation of the KLOX BioPhotonic OraLum Gel With a LED Curing Lamp in Moderate to Severe Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02325570 Completed KLOX Technologies Inc. 2015-03-31
NCT02283515 Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02283515 Completed Government Dental College and Research Institute, Bangalore 2014-06-30
NCT02218515 Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft https://ClinicalTrials.gov/show/NCT02218515 Completed Marmara University 2012-09-30
NCT02208739 Effect of Nonsurgical Periodontal Therapy Verses Oral Hygiene Instructions on Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02208739 Completed University of Malaya 2012-12-31
NCT02203812 Effect of Probiotic Lozenge on Gingivitis and Periodontitis https://ClinicalTrials.gov/show/NCT02203812 Completed CD Pharma India Pvt. Ltd. 2016-02-29
NCT02197260 Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing https://ClinicalTrials.gov/show/NCT02197260 Completed University of Geneva, Switzerland 2014-03-31
NCT02195765 Randomized Clinical Trial of Enamel Matrix Derivative: Radiographic Analysis https://ClinicalTrials.gov/show/NCT02195765 Completed University of Sao Paulo 2004-10-31
NCT02174757 Effect of Probiotic Inersan and Doxycycline in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02174757 Completed CD Pharma India Pvt. Ltd. 2014-11-30
NCT02174146 Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal Therapy https://ClinicalTrials.gov/show/NCT02174146 Completed Cairo University 2013-12-31
NCT02172716 Disruption of Immune Homeostasis in Type 2 Diabetics With Generalized Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02172716 Completed University of Sao Paulo 2015-05-31
NCT02170857 Effect of Hyaluronic Acid in the Treatment of Periodontal Pockets https://ClinicalTrials.gov/show/NCT02170857 Completed Damascus University 2016-02-29
NCT02168621 Intervention Study of Two Protocols for Non-surgical Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02168621 Active, not recruiting Göteborg University 2019-12-31
NCT02168543 1% Alendronate Gel in Treatment of Chronic Periodontitis Among Smokers https://ClinicalTrials.gov/show/NCT02168543 Completed Government Dental College and Research Institute, Bangalore 2011-01-31
NCT02160613 Osteoprotegerin Before and After Periodontal Surgery https://ClinicalTrials.gov/show/NCT02160613 Completed Cairo University 2013-12-31
NCT02126267 Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection https://ClinicalTrials.gov/show/NCT02126267 Completed Centro Universitario de Lavras 2014-02-28
NCT02121665 Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients. https://ClinicalTrials.gov/show/NCT02121665 Completed CD Pharma India Pvt. Ltd. 2016-01-31
NCT02120872 Platelet Rich Fibrin Combined With Simvastatin for Treatment of Intrabony Defect in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02120872 Completed Government Dental College and Research Institute, Bangalore 2014-01-31
NCT02066337 Effect of Ozone Gel on Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02066337 Completed October 6 University 2014-01-31
NCT02060032 1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02060032 Completed Government Dental College and Research Institute, Bangalore 2013-11-30
NCT01282229 Study to Compare Laser Assisted New Attachment Procedure (LANAP) to Traditional Treatments of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01282229 Completed Institute for Advanced Laser Dentistry 2014-03-31
NCT02033226 Clinical, Anti-Inflammatory And Anti-Infective Properties Of Amniotic Membranes Used For Guided Tissue Regeneration https://ClinicalTrials.gov/show/NCT02033226 Completed SVS Institute of Dental Sciences 2013-02-28
NCT02014532 Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02014532 Completed Tatyasaheb Kore Dental College 2013-07-31
NCT02013323 Clinical and Microbiological Efficacy of Systemic Ayurvedic Immunomodulator Septilin in the Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02013323 Completed Government Dental College and Research Institute, Bangalore 2013-08-31
NCT01997853 Omega-3 Fatty Acids in Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT01997853 Completed Tatyasaheb Kore Dental College 2013-08-31
NCT01997814 Role of Herbal Immunomodulators in the Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01997814 Completed Tatyasaheb Kore Dental College 2013-07-31
NCT01951547 The Periodontal Disease and Diabetes Mellitus Interrelationship Among Adult Malaysians https://ClinicalTrials.gov/show/NCT01951547 Completed University of Malaya 2011-12-31
NCT01945632 Effect of Root Planing on Surface Topography. https://ClinicalTrials.gov/show/NCT01945632 Completed Universidad de Granada 2013-01-31
NCT01938183 Full-mouth Periodontal Debridement and Metronidazole Gel in Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01938183 Completed University of Campinas, Brazil 2010-03-31
NCT01929135 Short-term Effect of 2% Atorvastatin Dentifrice in Periodontal Status. https://ClinicalTrials.gov/show/NCT01929135 Completed Universidad de los Andes, Chile 2014-01-31
NCT01921738 The Effect of Azithromycin in the Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01921738 Completed Isfahan University of Medical Sciences 2013-03-31
NCT01904422 Periodontal Treatment in Non-controlled Type 2 Diabetes Mellitus Patients. Clinical Trial https://ClinicalTrials.gov/show/NCT01904422 Completed Universidad de los Andes, Chile 2015-12-31
NCT01870362 Efficacy of a Probiotic Lozenge (Inersan) in Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01870362 Completed CD Pharma India Pvt. Ltd. 2014-07-31
NCT01837199 MTZ Plus AMX in the Treatment of Smokers and Non-smokers https://ClinicalTrials.gov/show/NCT01837199 Completed University of Guarulhos 2012-12-31
NCT01647282 Local Minocycline to Reduce Future Inflammation and Bone Loss in Periodontal Maintenance Patients https://ClinicalTrials.gov/show/NCT01647282 Completed University of Nebraska 2015-12-31
NCT01642641 Different Surgical Modalities in the Treatment of Periodontitis https://ClinicalTrials.gov/show/NCT01642641 Recruiting Queen Mary University of London 2021-04-30
NCT01568944 Role of Infected Blood Dendritic Cells in Heart Disease Risk https://ClinicalTrials.gov/show/NCT01568944 Completed Augusta University 2014-09-30
NCT01535690 Photodynamic Therapy Associated With Full-mouth Ultrasonic Debridement in the Treatment of Severe Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01535690 Completed Escola Bahiana de Medicina e Saude Publica 2009-10-31
NCT01499225 A Clinical Trial of YH14642 in Patients With Chronic Periodontal Disease https://ClinicalTrials.gov/show/NCT01499225 Completed Yuhan Corporation 2013-07-31
NCT01438333 Efficacy of INERSAN in Patients With Chronic Periodontitis as Adjunctive to Full Mouth Disinfection https://ClinicalTrials.gov/show/NCT01438333 Completed University of L’Aquila 2015-03-31
NCT01433744 Short-term Changes on C-Reactive Protein (CRP) Levels After Non-surgical Periodontal Treatment https://ClinicalTrials.gov/show/NCT01433744 Completed State University of Maringá 2011-07-31
NCT04425343 Microbial Profiling in Pockets Related to Chronic Periodontitis Patients Using 16s RNA Metagenomics Sequencing https://ClinicalTrials.gov/show/NCT04425343 Completed Ajman University 2018-09-15
NCT04374383 Novel Photosensitizer in The Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT04374383 Recruiting SVS Institute of Dental Sciences 2020-11-30
NCT04355416 Clinical and Anti-inflammatory Effect of Curcumin Oral Gel as Adjuncts in Treatment of Periodontal Pocket https://ClinicalTrials.gov/show/NCT04355416 Recruiting University of Baghdad 2020-05-30
NCT04339309 Comparison Between Two Non-surgical Periodontal Treatment Procedures With and Without Interdental Hygiene Devices in Periodontitis Patients: a Longitudinal Prospective Controlled Clinical Trial https://ClinicalTrials.gov/show/NCT04339309 Completed Cairo University 2016-07-31
NCT04332965 Periostin and Non-Surgical Periodontal Treatment https://ClinicalTrials.gov/show/NCT04332965 Completed Kırıkkale University 2018-01-31
NCT04264624 Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis https://ClinicalTrials.gov/show/NCT04264624 Completed Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 2019-10-05
NCT04223869 IL-34 Levels in Various Types of Periodontitis https://ClinicalTrials.gov/show/NCT04223869 Completed Bulent Ecevit University 2016-02-29
NCT04207034 Effect of the Diode Laser on Bacteremia Associated With Periodontal Flap Surgery: A Clinico-Microbiological Study https://ClinicalTrials.gov/show/NCT04207034 Enrolling by invitation Krishnadevaraya College of Dental Sciences & Hospital 2020-04-30
NCT04149834 Clinical and Radiographic Evaluation of NIPSA Versus M-MIST in Treatment of Intra-osseous Defects https://ClinicalTrials.gov/show/NCT04149834 Recruiting Cairo University 2021-12-01
NCT04082949 Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT04082949 Completed Inonu University 2018-12-10
NCT04076098 Locally Delivered Minocycline in Advanced Periodontitis https://ClinicalTrials.gov/show/NCT04076098 Recruiting Mahsa University 2020-06-30
NCT04074915 Effects of Herbal Mouth Rinse for Chronic Periodontitis https://ClinicalTrials.gov/show/NCT04074915 Completed Institute of Dental Sciences, Bareilly, Uttar Pradesh, India 2019-04-15
NCT04020458 Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant https://ClinicalTrials.gov/show/NCT04020458 Enrolling by invitation Augusta University 2020-11-09
NCT03915730 Smoking and Peptidoglycan Recognition Protein-1 and Initial Periodontal Therapy https://ClinicalTrials.gov/show/NCT03915730 Completed Kırıkkale University 2017-07-31
NCT03882138 Influence of Gingival Biotype on the Outcome of Open Flap Debridement https://ClinicalTrials.gov/show/NCT03882138 Completed Postgraduate Institute of Dental Sciences Rohtak 2019-02-28
NCT03874390 Effects of Ozone Therapy on Clinical Parameters and Inflammatory Cytokines in Chronic Periodontitis Patients https://ClinicalTrials.gov/show/NCT03874390 Completed Ataturk University 2015-10-31
NCT03863249 Use of the xCELLigence System for Quantification of Bacterial Biofilm’s Real Time Formation and Antibiotics Selection. https://ClinicalTrials.gov/show/NCT03863249 Recruiting University of Valencia 2019-08-31
NCT03851757 Cleansing Efficacy of Waist-shaped Interdental Brushes. https://ClinicalTrials.gov/show/NCT03851757 Completed Medical University Innsbruck 2018-03-02
NCT03836781 Teh Effect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist https://ClinicalTrials.gov/show/NCT03836781 Completed Islamic Azad University, Tehran 2019-06-08
NCT03810560 Erbium Chromium: YSGG Laser Effect on Surgical Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03810560 Active, not recruiting Ain Shams University 2019-03-31
NCT03807596 Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2 https://ClinicalTrials.gov/show/NCT03807596 Completed Cairo University 2017-06-29
NCT03791099 Porous Metronidazole Loaded Matrix for Local Treatment of Periodontitis. https://ClinicalTrials.gov/show/NCT03791099 Active, not recruiting Wroclaw Medical University 2019-01-31
NCT03783845 The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients https://ClinicalTrials.gov/show/NCT03783845 Completed Taibah University 2016-03-01
NCT03745300 Comparative Evaluation Of 1.2% Atorvastatin and 1.2% Simvastatin Gel Local Drug Delivery And Redelivery In Chronic Periodontitis Subjects With Diabetes Mellitus: A Randomized Controlled Clinical Trial. https://ClinicalTrials.gov/show/NCT03745300 Completed Government Dental College and Research Institute, Bangalore 2017-12-22
NCT03741374 Minimally-invasive Non-surgical Therapy of Intrabony Defects https://ClinicalTrials.gov/show/NCT03741374 Recruiting Queen Mary University of London 2022-12-31
NCT03692819 Antibiotic and Probiotic Therapies in the Adjuvant Treatment of the Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT03692819 Enrolling by invitation Universidade Estadual Paulista Júlio de Mesquita Filho 2020-02-20
NCT03677297 “Efficacy Of 1.2% Rosuvastatin Gel In The Management Of Infrabony Defects” https://ClinicalTrials.gov/show/NCT03677297 Completed Dr. D. Y. Patil Dental College & Hospital 2017-08-01
NCT03656484 New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin https://ClinicalTrials.gov/show/NCT03656484 Completed Concordia Dent Srl 2019-12-20
NCT03628872 Treatment of Periodontitis With Er:YAG Laser https://ClinicalTrials.gov/show/NCT03628872 Completed Columbia University 2019-05-01
NCT03599401 Effect of Aspirin Vs Omega 3 Fatty Acid After Scaling and Root Planing in Type II Diabetic Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03599401 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2017-01-15
NCT03554187 Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03554187 Recruiting Pileje 2019-05-22
NCT03553095 Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03553095 Active, not recruiting University of Alabama at Birmingham 2019-12-30
NCT03533972 Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis https://ClinicalTrials.gov/show/NCT03533972 Completed Tatyasaheb Kore Dental College 2018-02-27
NCT03519152 To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery https://ClinicalTrials.gov/show/NCT03519152 Completed Tatyasaheb Kore Dental College 2017-05-20
NCT03516370 Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03516370 Completed Tatyasaheb Kore Dental College 2018-03-26
NCT03499184 Adjunctive Probiotics in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03499184 Completed Ziauddin Hospital 2018-09-01
NCT03498404 Evaluation of Antimicrobial Photodynamic Therapy in Multiple Applications as a Coadjuvant in the Surgical Therapy of Access to Scaling https://ClinicalTrials.gov/show/NCT03498404 Completed University of Sao Paulo 2018-04-07
NCT03475394 Effectiveness of Locally Delivered Morus Alba Gel on Moderate Periodontitis https://ClinicalTrials.gov/show/NCT03475394 Completed KLE VK Institute of Dental Sciences 2015-09-30
NCT03453476 Effect of Photodynamic Therapy on Gingival Crevicular Cytokines in Periodontitis Patients https://ClinicalTrials.gov/show/NCT03453476 Completed National University, Singapore 2013-03-31
NCT03444350 Use of the Ozone in Periodontal Treatment https://ClinicalTrials.gov/show/NCT03444350 Completed Çanakkale Onsekiz Mart University 2015-05-23
NCT03432975 Evaluation of Multiple Subgingival Irrigations. https://ClinicalTrials.gov/show/NCT03432975 Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2019-08-31
NCT03419429 Simvastatin Gel With Perforated Resorbable Membranes in Treatment of Intrabony Defects in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03419429 Completed Ain Shams University 2017-06-30
NCT01249846 The Efficacy and Safety of 2.5 mg Chlorhexidine Gluconate Chip (PerioChip®) in Frequent Treatment Versus Routine Treatment in Therapy of Adult Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01249846 Completed Dexcel Pharma Technologies Ltd. NA
NCT01229631 The Effect of Daily Dietary Intake of Dried Juice Concentrates of Fruit, Vegetables and Berries Upon Outcomes of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01229631 Completed Birmingham Community Healthcare NHS 2017-06-30
NCT01211223 Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT01211223 Completed University of Chile 2011-03-31
NCT01040286 The Efficacy and Safety of Flurbiprofen Chip Versus Chlorhexidine Chip (Periochip®) in Therapy of Adult Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01040286 Completed Dexcel Pharma Technologies Ltd. NA
NCT01034501 Adjunctive Photodynamic Therapy in Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01034501 Completed University of Sao Paulo 2013-08-31
NCT00997178 Diabetes and Periodontal Therapy Trial https://ClinicalTrials.gov/show/NCT00997178 Completed Stony Brook University 2012-10-31
NCT04141033 Assessment of Neopterin Levels in Pre- and Post-menopausal Women With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT04141033 Completed Ain Shams University 2019-04-25
NCT02907528 Furcation Therapy With Enamel Matrix Derivative https://ClinicalTrials.gov/show/NCT02907528 Completed Ohio State University Comprehensive Cancer Center 2014-12-31
NCT03639636 is the Sclerostin Marker of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03639636 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2017-12-20
NCT03028727 Diode Laser Therapy As An Adjunct To Scaling And Root Planing https://ClinicalTrials.gov/show/NCT03028727 Completed KLE Society’s Institute of Dental Sciences 2013-09-30
NCT02808988 Changes of GCF Levels of RANKL and Osteoprotegerin in Postmenopausal Osteoporosis https://ClinicalTrials.gov/show/NCT02808988 Completed Ondokuz Mayıs University 2015-10-31
NCT00805558 Comparison of Moxifloxacin With Ciprofloxacin/Metronidazole on Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT00805558 Completed Facultad Nacional de Salud Publica 2009-12-31
NCT02580331 1% Metformin Gel in the Treatment of Class II Furcation Defects https://ClinicalTrials.gov/show/NCT02580331 Completed Government Dental College and Research Institute, Bangalore 2015-09-30
NCT02738515 Boric Acid in Degree 2 Furcation Defect https://ClinicalTrials.gov/show/NCT02738515 Completed Government Dental College and Research Institute, Bangalore 2016-02-29
NCT02372656 Simvastatin and Metformin in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02372656 Completed Government Dental College and Research Institute, Bangalore 2014-08-31
NCT02248103 Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony Defects https://ClinicalTrials.gov/show/NCT02248103 Completed Cairo University 2014-04-30
NCT01917292 Impact of Periodontal Intervention on Vascular Dysfunction https://ClinicalTrials.gov/show/NCT01917292 Completed First Affiliated Hospital, Sun Yat-Sen University 2013-12-31
NCT04038801 Full-mouth Treatment Approaches in Severe Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT04038801 Completed Aydin Adnan Menderes University 2008-05-30
NCT00669253 Treatment of Periodontitis Using Er:YAG Laser vs. Conventional Treatment Modalities https://ClinicalTrials.gov/show/NCT00669253 Completed University Hospital, Ghent 2010-12-31
NCT00668746 Long-term Safety of Minocycline in Patients With Gum Disease https://ClinicalTrials.gov/show/NCT00668746 Completed OraPharma 2009-02-28
NCT00529555 Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis https://ClinicalTrials.gov/show/NCT00529555 Completed Sunstar Americas 2008-12-31
NCT00425451 The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis https://ClinicalTrials.gov/show/NCT00425451 Completed Dexcel Pharma Technologies Ltd. 2009-01-31
NCT00336661 PerioWave Re-Treatment Protocol Compared to Scaling and Root Planing (SRP) and a Single Treatment With PerioWave https://ClinicalTrials.gov/show/NCT00336661 Completed Ondine Research Laboratories NA
NCT00297518 Study of Scaling and Root Planing (SRP) With PerioWave vs. SRP Alone in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT00297518 Completed Ondine Research Laboratories NA
NCT02851823 Combined Use of Er:YAG and Nd:YAG Laser https://ClinicalTrials.gov/show/NCT02851823 Completed Izmir Katip Celebi University 2015-10-31
NCT00221130 Clinical Trials of Regeneration for Periodontal Tissue https://ClinicalTrials.gov/show/NCT00221130 Completed Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03391349 Quantification of Proteomes: L-plastin , Lipocalin and Adiponectin in Chronic Periodontitis and Diabetic Subjects https://ClinicalTrials.gov/show/NCT03391349 Completed Meenakshi Ammal Dental College and Hospital 2017-07-22
NCT03369405 Thyroid Disease and Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03369405 Active, not recruiting University at Buffalo 2021-08-01
NCT03297749 Genetic Variants and Oxidative Stress as Links Between Periodontitis and Metabolic Syndrome https://ClinicalTrials.gov/show/NCT03297749 Active, not recruiting University College, London 2017-09-30
NCT03240666 Protozoans in Biofilm From Patients With Periodontitis https://ClinicalTrials.gov/show/NCT03240666 Recruiting Central Hospital, Nancy, France 2019-04-10
NCT03225950 Interaction Between Immune Cells and Bacteria Associated With Periodontitis https://ClinicalTrials.gov/show/NCT03225950 Completed University of Copenhagen 2018-10-12
NCT03178838 Clinical Study of the Presence of Trichomonas Tenax and Entamoeba Gingivalis in Patients With Periodontitis https://ClinicalTrials.gov/show/NCT03178838 Completed Central Hospital, Nancy, France 2014-11-11
NCT03171675 Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03171675 Completed Ain Shams University 2015-03-02
NCT03128502 Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease https://ClinicalTrials.gov/show/NCT03128502 Completed Cairo University 2017-02-28
NCT03041480 Serum Lipid Levels and Lp-PLA2 in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03041480 Completed Meenakshi Ammal Dental College and Hospital 2015-08-23
NCT02833285 B Cell Functions in Periodontitis https://ClinicalTrials.gov/show/NCT02833285 Recruiting University Hospital, Brest 2020-09-30
NCT02521688 Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery https://ClinicalTrials.gov/show/NCT02521688 Completed Ain Shams University 2015-07-31
NCT02503046 Estimation of Pentraxin3 and PGingivalis Levels in Patients With Knee Joint and Gum Diseases https://ClinicalTrials.gov/show/NCT02503046 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2015-11-30
NCT02498938 The Association of SERPINA1 Gene Disturbance in Patients With Lung and Gum Disorders https://ClinicalTrials.gov/show/NCT02498938 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2015-11-30
NCT02467283 Gene Expression Profiles in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02467283 Completed Kocaeli University 2015-08-31
NCT02441920 Chronic Periodontitis and Tooth Loss in Patients With Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT02441920 Active, not recruiting University of Birmingham 2012-11-30
NCT02394860 Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension https://ClinicalTrials.gov/show/NCT02394860 Recruiting University Hospital, Strasbourg, France 2020-05-31
NCT02280122 Activated MMP-8 as Diagnostic Test for Periodontitis https://ClinicalTrials.gov/show/NCT02280122 Completed Goethe University 2014-02-28
NCT02273128 A Study to Assess the Disturbances in Calcitonin Gene in Patients With Gum Disease and Osteoporosis https://ClinicalTrials.gov/show/NCT02273128 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2014-10-31
NCT02127346 Relationship Between Chronic Periodontitis and Vitamin D and Calcium in Men https://ClinicalTrials.gov/show/NCT02127346 Completed Damascus University 2015-08-31
NCT02127203 Nitro-oxidative Stress in Periodontitis https://ClinicalTrials.gov/show/NCT02127203 Completed Damascus University 2015-09-30
NCT02111005 Smoking Influence on Apoptosis in Periodontitis https://ClinicalTrials.gov/show/NCT02111005 Completed Damascus University 2015-12-31
NCT01467674 The Effect Of Glycemic Control On Malondialdehyde, Glutathione Peroxidase, Glutathione And Paraoxonase https://ClinicalTrials.gov/show/NCT01467674 Completed Suleyman Demirel University 2009-05-31
NCT04240015 Association of Periodontitis With Oral Health Related Quality of Life https://ClinicalTrials.gov/show/NCT04240015 Completed Baskent University 2014-01-10
NCT04127487 Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects https://ClinicalTrials.gov/show/NCT04127487 Recruiting Meenakshi Ammal Dental College and Hospital 2020-11-01
NCT04127474 Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease https://ClinicalTrials.gov/show/NCT04127474 Recruiting Meenakshi Ammal Dental College and Hospital 2019-12-20
NCT04115176 GCF IL-17 Levels and Oxidative Status of Smoking and Non-smoking Individuals With Periodontitis https://ClinicalTrials.gov/show/NCT04115176 Completed Ondokuz Mayıs University 2019-07-10
NCT04047212 Metagenomic Analysis of the Link Between Periodontitis and Smoking https://ClinicalTrials.gov/show/NCT04047212 Completed Cairo University 2019-10-12
NCT03786133 Chronic Periodontitis Microbiota in Type 2 Diabetes Mellitus Patients https://ClinicalTrials.gov/show/NCT03786133 Completed University of Bologna 2016-07-26
NCT03727035 Quantification of CD163 Inflammatory Biomarker in Chronic Periodontitis and Diabetic Subjects https://ClinicalTrials.gov/show/NCT03727035 Recruiting Meenakshi Ammal Dental College and Hospital 2019-11-30
NCT03721159 Quantification of Micro-RNA 146-a in Chronic Periodontitis and Coronary Heart Disease Subjects https://ClinicalTrials.gov/show/NCT03721159 Completed Meenakshi Ammal Dental College and Hospital 2018-09-01
NCT03644901 Assessment of Response to the Conventional Periodontal Treatment Based on the Blood Group Phenotypes. https://ClinicalTrials.gov/show/NCT03644901 Completed Damascus University 2018-10-01
NCT03631498 Apoptotic Changes in Gingiva Caused by Smoking https://ClinicalTrials.gov/show/NCT03631498 Completed Tokat Gaziosmanpasa University 2018-01-10
NCT03625414 Tissue Alterations in Aggressive and Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03625414 Completed Tokat Gaziosmanpasa University 2018-02-01
NCT03621891 Alterations in Subgingival Microbiota and Hypoxia in Occlusal Trauma https://ClinicalTrials.gov/show/NCT03621891 Completed Tokat Gaziosmanpasa University 2017-05-01
NCT03426241 Effect of Smoking on the Expression of Gelatinases in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03426241 Completed Baskent University 2012-12-29
NCT01233765 Analysis of Neutrophil Response in Chronic Periodontitis https://ClinicalTrials.gov/show/NCT01233765 Completed Birmingham Community Healthcare NHS 2015-06-30
NCT03371446 DNA Methylation Profile of the SOCS-1 Gene Promoter in Smokers Patients With Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT03371446 Completed University of Sao Paulo 2017-10-16
NCT02190773 Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System https://ClinicalTrials.gov/show/NCT02190773 Completed Hacettepe University 2013-04-30

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02954120 Chronic Periodontitis and Polycystic Ovary Syndrome https://ClinicalTrials.gov/show/NCT02954120 Completed Bezmialem Vakif University 2015-05-31
NCT02304497 PRF Growth Factors Levels in Diabetic Patients With Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02304497 Completed Bulent Ecevit University 2014-07-31
NCT04277390 microRNA 155 Levels and Periodontal Microflora (Bacteria and Virus) in Preeclampsia. https://ClinicalTrials.gov/show/NCT04277390 Completed Meenakshi Ammal Dental College and Hospital 2018-08-20
NCT03803176 Tissue Plasminogen Activator & Plasminogen Activator Inhibitor Type-1 In Gingival Tissues Of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT03803176 Completed Cairo University 2018-06-11
NCT03345745 Saliva Levels of S100A12, CRP, Fetuin-A in Periodontal Disease Patients https://ClinicalTrials.gov/show/NCT03345745 Completed T.C. ORDU ÃœNÄ°VERSÄ°TESÄ° 2017-06-01